Nature Biotech Correspondence Link 5 years ago if you seriously wanted a good protein, you wouldn't start with computational modeling, but in the last year lines became more and more blurred. Today, if i want a better protein X, do i start with a model or library design? How would each of them explore the sequence space? How would it bias the search? What would be faster? What types of tasks should prioritize one over the other? We don't know! This transition period requires a bunch of ad h...| lada nuzhna
The semiconductor industry will soon abandon its pursuit of Moore's law. Now things could get a lot more interesting.| Nature News & Comment
Two studies show the extent of gunshot wounds inflicted by police and link certain police-department policies with a lower death toll.| www.nature.com
This could be a very important result, but it needs replication: it’s a small study, relies on self-reporting of food consumed, and uses p-values (why do Nature journals still permit this?).| lee-phillips.org
Once upon a time, many, many years ago, a man found a closed fruit jar containing a honeybee. When he drank the contents, he tasted a new, strange flavor. Suddenly his head was spinning, he laughed for no reason, and he felt powerful. He drank all the liquid in the jar. The next day he experienced an awful feeling. He had a headache, pain, an unpleasant taste in his mouth, and dizziness — he had just discovered the hangover. You might think this is just a tale, but is it? Several archaeolog...| www.nature.com
‘Sneeze neurons’ activated by triggers such as pollen or a viral infection send an achoo signal, whereas cough neurons induce a hack.| www.nature.com
IL-11 is identified as a key regulator of ERK–AMPK–mTORC1 signalling, metabolism, inflammation and age-related disease and lifespan in mouse and human.| Nature
Quantification of climate warming in California using machine learning shows increased daily wildfire growth risk by 25%, with an expected increase of 59% and 172% in 2100, for low- and very-high-emissions scenarios, respectively.| Nature
Individuals with long COVID show marked biological changes in cortisol and immune factors relative to convalescent populations.| Nature
Solar hydrogen production devices have demonstrated promising performance at the lab scale, but there are few large-scale on-sun demonstrations. Here the authors present a thermally integrated kilowatt-scale pilot plant, tested under real-world conditions, for the co-generation of hydrogen and heat.| Nature
Computer scientists must identify sources of bias, de-bias training data and develop artificial-intelligence algorithms that are robust to skews in the data.| www.nature.com
Nature Biotechnology - Lessons from human teratomas to guide development of safe stem cell therapies| Nature
The International Congress on Recombinant DNA Molecules, held in 1975 at the Asilomar Conference Center in Pacific Grove, California, broke new ground. In a poacher-turned-gamekeeper sort of a way. At Asilomar the scientists in the vanguard of genetic engineering research brought the public's attention to the potential dangers of their work, but at the same time they established a set of stringent guidelines to ensure public safety. Paul Berg, who — with David Baltimore, Sydney Brenner, Ric...| Nature
A reinforcement learning approach based on AlphaZero is used to discover efficient and provably correct algorithms for matrix multiplication, finding faster algorithms for a variety of matrix sizes.| Nature
Transitioning the global energy system to renewables will likely expand energy transition minerals and metals (ETMs) projects to sensitive territories. Across 5,097 projects globally, greater than half of the ETM resource base appears to be located on or near the lands of Indigenous and peasant peoples whose rights to consultation are embedded in United Nations declarations.| Nature