Psilocybin is the most well-known compound found in psychedelic mushrooms (aka psilocybin mushrooms or magic mushrooms). It is a substituted tryptamine and prodrug of psilocin, and the compound that…| Psychedelic Science Review
Psilocin, and not psilocybin, is actually responsible for the psychedelic effects of magic mushrooms. The body converts the prodrug psilocybin into psilocin.| Psychedelic Science Review
Using validated behavior models and known standards, studies are finding significant differences between male and female rodents given psychedelic drugs.| Psychedelic Science Review
Nichols and Frescas’ 1999 hypothesis becomes a validated scientific theory.| Psychedelic Science Review
Norpsilocin is not psychoactive but minor changes to its chemical structure translate into major changes in its pharmacology.| Psychedelic Science Review
Companies are deconstructing magic mushroom cocktails in search of therapeutic medicines.| Psychedelic Science Review
Magic mushroom science marches on as understudied psilocybin derivatives start taking center stage.| Psychedelic Science Review
In the last 10 years, psychiatric interest in the use of psychedelics, such as psilocybin and LSD, has surged. A new study employed mice to examine how LSD could exert changes on the inflammatory…| Psychedelic Science Review
Can the meteoric rise of psychedelics and entactogens clear the legal hurdles of abuse potential assessment and rescheduling?| Psychedelic Science Review
Psychedelic drugs like LSD powerfully alter consciousness and promote neural plasticity, but drug tolerance occurs rapidly following the first dose. Although the mechanisms that underlie psychedelic…| Psychedelic Science Review
Psychedelic trips often unfold without issues, but what if a trip needs to be stopped? Drugs such as benzodiazepines and antipsychotics are recommended as rescue medications and have been around for…| Psychedelic Science Review
Lab grown brains help to shed insight on 5-MeO-DMT mechanisms.| Psychedelic Science Review