When columnist Dagmar Munn's special footwear began to wear out, she went shoe shopping — which required a certain amount of resilience.| ALS News Today
Researchers genetically reprogrammed mouse nerve cells to reverse cell aging, delaying the onset of ALS symptoms in the animals.| ALS News Today
A repurposed veterinary medication, NUZ-001, helped ALS patients live longer and slowed disease progression in a long-term study.| ALS News Today
A brain-computer interface that can translate silent thoughts into spoken words may help speech-impaired people, including those with ALS.| ALS News Today
A new analysis found Radicava ORS (edaravone) slows functional decline and helps adults with amyotrophic lateral sclerosis (ALS) live longer.| ALS News Today
Due to a lack of resources and personnel, the FDA has delayed until October its decision on lifting a clinical hold on ALS drug NUZ-001.| ALS News Today
The ALS therapy ATH-1105 entered the brain and spinal cord at dose-proportional levels in healthy volunteers, and had a good safety profile.| ALS News Today
Coya Therapeutics got FDA clearance for a Phase 2 trial in the U.S. to investigate COYA 302 as an ALS treatment.| ALS News Today
Researchers have developed a blood-based test that shows high accuracy for diagnosing ALS as early as up to 10 years before symptom onset.| ALS News Today
This year's ALS Nexus conference allowed the community to connect with each other, celebrate recent advances, and share hope for the future.| ALS News Today
U.S. and China regulators have now cleared Sineugene Therapeutics' ALS gene therapy SNUG01 for clinical trials.| ALS News Today
Managing her husband Todd's health needs means continuing to improve the processes for his ALS caregivers, writes columnist Kristin Neva.| ALS News Today
Columnist Kristin Neva and her husband, Todd, marked the 15-year anniversary of his ALS diagnosis with a rare outing and outdoor lunch.| ALS News Today
Electric bidets are popular among people with ALS, writes columnist Dagmar Munn, who first encountered one in Japan and is now a fan.| ALS News Today
A trial that will test a noninvasive device called MyoRegulator as a treatment for ALS was cleared to start enrolling patients in the U.S.| ALS News Today
Strategies being explored as treatments for ALS might also be useful in the treatment of Huntington's disease, a study suggested.| Huntington's Disease News
Radicava (edaravone) is an approved infusion therapy used to slow functional decline in people with amyotrophic lateral sclerosis (ALS).| ALS News Today
Various adaptations and equipment are available that can help a person with ALS eat, dress, use the bathroom, and move around.| ALS News Today
The FDA has granted orphan drug status to Actimed Therapeutics' S-oxprenolol, a treatment candidate that aims to ease muscle wasting in ALS.| ALS News Today
Woolsey received three new U.S. patents covering innovations related to ROCK inhibitor Bravyl (oral fasudil), its investigational ALS drug.| ALS News Today
The analyses offer evidence for a slowing of functional decline and improved survival outcomes with long-term Radicava ORS by ALS patients.| ALS News Today
Neither memantine nor trazodone was able to slow amyotrophic lateral sclerosis (ALS) disease progression in a platform clinical trial.| ALS News Today
An analysis in 62 ALS patients who followed the Phase 2b study's rules (protocol) found a 37.4% ALSFRS-R difference with PrimeC vs. placebo.| ALS News Today
ALS speech problems are caused by a weakening of the muscles of the mouth and throat and worsen over time as the disease progresses.| ALS News Today
Exercise has multiple benefits for people with ALS, such as preserving muscle strength and mobility, and increasing overall quality of life.| ALS News Today
Columnist Dagmar Munn explains how she moved on from a mindset of "why bother?" after her ALS diagnosis. It helps her to live well.| ALS News Today
Two ALS centers launched an initiative to expand access to clinical trials and accelerate improvements in ALS research.| ALS News Today
After columnist James Clingman's ALS diagnosis, he says he feared sleep. Now, it's a welcome escape to a world of late family and friends.| ALS News Today
What columnist Dagmar Munn thought was an ALS symptom was just an impostor. "Learned nonuse" was her true problem, and she addressed it.| ALS News Today
An ALS diagnosis requires testing for signs of the neurodegenerative disease that rules out other disorders with similar symptoms.| ALS News Today
The scientists believe the algorithm they developed could be used to help patients and doctors make better treatment and care plans.| ALS News Today
A gene therapy to increase nerve cell connectivity worked to ease motor dysfunction in an ALS mouse model but did not prolong survival.| ALS News Today
Mutant huntingtin protein may drive nerve cell death by poking holes in the membrane that surrounds and protects cells' DNA-filled core.| Huntington's Disease News
ALS is a neurodegenerative condition that causes muscle weakness, movement problems, and breathing issues. Learn more about ALS symptoms here.| ALS News Today
About 90% of cases of amyotrophic lateral sclerosis (ALS) are characterized as sporadic ALS, meaning they occur spontaneously.| ALS News Today
The European Commission has approved Qalsody to treat ALS patients in the EU whose disease is associated with mutations in the SOD1 gene.| ALS News Today
The FDA granted conditional approval to tofersen, now Qalsody, for the treatment of ALS associated with mutations in the SOD1 gene.| ALS News Today
Qalsody (tofersen) is conditionally approved in the U.S. as treatment for amyotrophic lateral sclerosis associated with SOD1 gene mutations.| ALS News Today
When more than one person in the same biological family is affected by amyotrophic lateral sclerosis (ALS), it is known as familial ALS.| ALS News Today
PrimeC slowed lung function decline and complication-free survival when treatment started early, per data from a Phase 2b ALS clinical trial.| ALS News Today
Starting treatment with PrimeC six months sooner was associated with slower disease progression and a survival benefit for ALS patients.| ALS News Today
ALS is a neurodegenerative condition that affects motor neurons. Learn about the causes and risk factors of ALS.| ALS News Today
Inspired by the Olympic athletes at the 2024 Paris Games, columnist Dagmar Munn shares the lessons she's applying to her life with ALS.| ALS News Today
Elevated blood and urine levels of metals like copper, selenium, and zinc raised disease risk by 3 times, and shortened patients' lives.| ALS News Today
ALS is a neurodegenerative disorder marked by progressively worsening muscle weakness and neurological dysfunction.| ALS News Today
CNM-Au8 is an experimental liquid treatment for people with ALS that intends to increase cell energy.| ALS News Today
A brain-computer interface allowed a man with amyotrophic lateral sclerosis to communicate through a computer that used his own voice.| ALS News Today
While traveling with friends, columnist Juliet Taylor is reminded of the importance of living out loud, especially in the face of ALS.| ALS News Today
A Penn State University researcher will use the $250,000 to identify and develop neuroprotective small molecules for ALS and like diseases.| ALS News Today
The selenium elevations with Qalsody may reflect a change in the antioxidant status of nerve cells, but more research is needed.| ALS News Today
Work using a new imaging technique found changes in how the SOD1 protein links with metal ions that seem key for how mutant SOD1 drives ALS.| ALS News Today
PrimeC led to improvements in iron accumulation in people with amyotrophic lateral sclerosis (ALS) in a clinical trial, new data showed.| ALS News Today
Clene submitted new data on CNM-Au8 to the FDA ahead of an upcoming meeting to discuss potential accelerated approval for the ALS therapy.| ALS News Today
The risk of death was nearly 60% lower in ALS patients given the experimental oral therapy CNM-Au8 than for an external placebo group, data show.| ALS News Today
Work in a Rett cell model found the potential gold nanocrystal therapy significantly improved mitochondrial function and neuronal health.| Rett Syndrome News
The FDA has approved a Phase 2 trial to test SPG601, an oral treatment candidate, in men with fragile X syndrome.| Fragile X News Today
MS is an autoimmune disease that affects the central nervous system. Learn more about MS types, causes, symptoms, diagnosis, and treatment.| Multiple Sclerosis News Today