We are a group of 53 individuals with Long COVID from across the U.S. In 2023, we joined a Long COVID clinical trial for Vyvgart (efgartigimod), a drug approved by the Food and Drug Administration (FDA) for the autoimmune disease myasthenia gravis. Without warning, the trial was canceled in June 2024. The post Vyvgart brought us back to life, but the Long COVID trial was canceled. We are calling on the NIH and HHS to study the drug. first appeared on The Sick Times.| The Sick Times
The World Wide Web has proven to be a transformative communication technology (we are using it right now). At the same time there have been some rather negative unforeseen consequences. Significantly lowering the threshold for establishing a communications outlet has democratized content creation and allows users unprecedented access to information from around the world. But it has also lowered the threshold for […] The post The Problem with Predatory Journals first appeared on Science-Base...| Science-Based Medicine
UAMS is ranked in the top 25% of participating clinics. The Winthrop P. Rockefeller Cancer Institute is a top participant in the National Cancer Institute’s TMIST (Tomosynthesis Mammographic Imaging Screening Trial). The study, which continues through 2027, compares two standard breast cancer screening methods — tomosynthesis (3D) mammograms and digital (2D) mammograms — and is designed to […]| Winthrop P. Rockefeller Cancer Institute
Clinical Trial for Drug to Battle Myeloma Underway at the UAMS Myeloma Center Carolina Schinke, M.D., is leading a clinical trial at the University of Arkansas for Medical Sciences (UAMS) Myeloma Center to study the effectiveness of a new myeloma-fighting drug, talquetamab. The trial is titled “A Phase 1/2, First-in-Human,…| Winthrop P. Rockefeller Cancer Institute
The blockchain is a distributed ledger technology (DLT) that allows transactions to be recorded in a permanent... The post Blockchain Technology for Healthcare: 6 Applications appeared first on Health Loops.| Health Loops
Traditionally, clinical trials have relied on paper-based consent forms to obtain participant approval. But this approach creates significant challenges. Administrative staff may misplace forms or spend unnecessary time on repetitive consent procedures, and participants often struggle to understand complex medical terminology. As clinical trial models continue to evolve, particularly with the growth of decentralized and… The post eConsent as the digital foundation for modern clinical trials...| Drug Discovery and Development
Static, one-size-fits-all clinical supply chains create waste, delay trial milestones and heighten compliance risk, pressures now intensified by the EU Clinical Trials Regulation. In response, biotechs are shifting from large safety stocks to flexible, data-driven, patient-centric models that pair real-time enrollment forecasting with agile labeling and regional depots. “The most critical KPI in a clinical… The post Q&A: Thermo Fisher’s Luke Wilson on hitting 100% dose delivery with pat...| Drug Discovery and Development
Volunteering for a clinical study or trial helps researchers discover new ways to diagnose, treat, and prevent Alzheimer’s disease. Nearly everyone can participate in clinical trials to ensure treatments benefit everyone. Study coordinators can answer questions about enrollment criteria, how long the study is, benefits of a trial, and more. Even if there isn’t a […] The post How Can I Find a Clinical Trial Near Me? appeared first on Illinois Cognitive Resources Network. Related posts: B...| Illinois Cognitive Resources Network
A new study that found the risk of Long COVID doubled in children following SARS-C0V-2 reinfection made mainstream headlines this week. The post Research updates, October 7 first appeared on The Sick Times.| The Sick Times
The vagus nerve, the longest cranial nerve in mammals, has emerged as a fascinating area of research in human medicine for its potential role in controlling chronic inflammation. This concept, known as the “cholinergic anti-inflammatory pathway,” suggests that vagal stimulation can reduce inflammatory responses throughout the body. As veterinary professionals increasingly seek novel approaches to […] The post The Vagus Nerve and Chronic Inflammation Control in Dogs appeared first on IVC...| IVC Journal
It looks likely we'll see oral GLP-1 drugs on the market by next year, with pharmaceutical company Eli Lilly reporting impressive results following a large, robust 72-week trial that saw obese participants lose an average of 27.3 lb, or 12.4% of their body weight with the once-daily pill.| New Atlas
A new study shows that a simple EEG signal, peak alpha frequency (PAF), may help track brain growth in Angelman syndrome. The post A new electroencephalogram (EEG) measure may help track brain growth in Angelman syndrome appeared first on Innovation District.| Innovation District
Researchers in Spain assessed over 190,000 participants, using data from a public health research network, in a study published in the journal Vaccines. They found that Long COVID prevalence was three to 10 times higher in individuals with three or more reported infections than in those with only one infection. The post Research updates, September 30 first appeared on The Sick Times.| The Sick Times
This perspective may be both interesting and disturbing from the standpoint of a scientist and student of science. Dr. Hazan claims to have been involved| BIOANALYTICX
The post MIND Matters | Quarterly Newsletter | Summer 2025 appeared first on UCI MIND.| UCI MIND
Today in STAT, my colleague and friend, Dr. Jason Karlawish from the University of Pennsylvania Memory Center offers “The way we talk about dementia is about to change completely.” The history of dementia care is less than ideal. Patients struggle to be seen by specialists and many if not most are not even diagnosed. Nihilism is rampant and the resources available to most patients and families on the journey of living with dementia are inadequate. Few treatments have achieved approval for...| UCI MIND
Curated by Fight CRC’s Medical Advisory Board & Research Advocacy Training and Support (RATS) team. Each month, we share a curated list of clinical trials and recent research that may support you as you explore treatment options. This month, our focus highlights emerging antibody-drug conjugates (ADCs), ctDNA-guided strategies, and TP53-targeted approaches that are shaping ... The post On Our Radar: This Month’s Clinical Trials Roundup appeared first on Fight CRC.| Fight CRC
When you hear “clinical trial,” you might picture endless paperwork or doctors tracking tumor scans. But here’s what you might not know: patients—people just like you—are also in the room where decisions get made.Through Fight CRC’s Research Advocacy Training & Support (RATS) program, survivors and caregivers are helping shape how studies are designed, who gets to join, and what outcomes really matter.This is your behind-the-scenes look at how patient advocates are changing resear...| Fight CRC
It turns out that AI really is doing the work. At least a growing chunk of it. Artificial intelligence is spreading through the global workforce like wildfire, dwarfing the adoption pace of the internet, with a new Anthropic report citing Gallup research that 40% of U.S. employees now use AI at work. While the field… The post As the pharma industry grapples with a talent shortfall, AI makes inroads in drug-safety workflows appeared first on Drug Discovery and Development.| Drug Discovery and Development
Drug Discovery and Development covers strategies and technologies related to pharmaceutical research and development and drug formulation.| Drug Discovery and Development
In veterinary medicine, the management of lower back pain, particularly due to radiculopathy, has seen significant advancements. This condition, characterized by the involvement of a spinal nerve, can result in debilitating pain and discomfort for our canine companions. Recently, a study explored a promising technique borrowed from human medicine: pulsed radiofrequency (PRF) therapy. Understanding Pulsed […] The post Advancements in Managing Canine Lumbosacral Pain with Pulsed Radiofrequenc...| IVC Journal
Clinical trials are built on safety, ethics, and careful oversight—especially for participants with conditions like ADHD and asthma.| Princeton Medical Institute
The following article has been written in response to a query. Query: Saeed Qureshi Let’s say you have two groups. One given the drug/treatment and| BIOANALYTICX
Colorectal cancer and mental health are two topics that make people extremely uncomfortable to talk about, but there shouldn’t be shame| Fight CRC
How biomarker discovery automation—spanning assay analytics, metadata capture, and data lineage—enables reproducible results across omics, imaging, and clinical data.| Drug Discovery and Development
Effective long-term follow-up in vaccine clinical trials is crucial. Explore key considerations for study design, patient tokenization, and regulatory compliance.| Drug Discovery and Development
First paragraph of text goes here until the bar below is green.| Fight CRC
Peter Barton Hutt, former Chief Counsel at the FDA and pioneer of medical device regulatory policy, joins as Plan A™ concludes successful trials. Los Angeles, CA – August 27, 2025 – NEXT Life Sciences, the modern reproductive healthcare company pioneering Plan A™, a first-of-its-kind, long-lasting, and on-demand-reversible male contraceptive, announced today the addition of renowned FDA […]| TechBullion
Novartis' therapy candidate ianalumab safely and effectively eased disease activity for adults with active Sjögren's in two clinical trials.| Sjogren's Disease News
The Ministry of Health will begin using real-world evidence like treatment outcomes from hospitals to inform drug listings in the MOH formulary, moving away from relying on clinical trial data alone in a shift towards value-based care and patient outcomes.| CodeBlue
The U.S. FDA has granted orphan drug designation to CS1, Cereno Scientific’s lead therapy candidate for treating pulmonary arterial hypertension (PAH).| Pulmonary Hypertension News
Novo Nordisk’s GLP-1 drug Wegovy expanded its label to include the metabolic disorder known as MASH. Analysts say there’s room for many MASH drugs with the treatment landscape expected to shape up to include combinations of therapies bringing different approaches to this fatty liver disease.| MedCity News
Investigators receive $5 million research grant to explore ways to use artificial intelligence to accelerate and improve screening and treatment for cardiovascular disease. The post American Heart Association funds Kaiser Permanente to study AI in cardiovascular care appeared first on Kaiser Permanente Division of Research.| Kaiser Permanente Division of Research
One global clinical trial testing astegolimab for moderate to severe COPD hit its main goal, but another did not, Genentech reports.| COPD News Today
“At the time of the episode,” Dr. Levin said at the conference, “Subject C didn’t recall it was her birthday. When prompted, she said, ‘I feel like an invalid.’” It was, he noted, a revealing momen…| The Skeptic's Kaddish 🇮🇱
Diverse clinical trials lead to better, safer treatments that reflect the real-world needs of all lupus patients. Here’s why – and how you can help make a difference. The post Why Diversity in Clinical Trials Matters for Lupus Patients Like You appeared first on CreakyJoints.| CreakyJoints
Eligibility, principal investigator, placebos, and informed consent — learning these key terms and more may help you understand and feel more confident about clinical trials. The post The Language of Clinical Trials appeared first on CreakyJoints.| CreakyJoints
On February 26, 2016, the first version of an article titled “How blockchain-timestamped protocols could improve the trustworthiness of medical science” was posted to F1000Research. The paper had two authors: Greg Irving of the University of Cambridge and John Holden of Garswood Surgery. The article describes a method for timestamping clinical trials, so the retrospective existence of a trial can be verified at a later date. The technique uses the Bitcoin blockchain as an immutable …| Satoshi Village
Research Science Liaisons – We’re like MSLs, Only the Opposite When we first meet with Medical Science Liaisons (MSLs), they are often confused about our role. We can’t blame them – our position is unique and very few cancer centers have a role like ours. Our 30-second “pitch” to MSLs is always “We are like […]| THE MSL
Immunotherapy is becoming a more prominent option for people with breast cancer, especially those with certain subtypes of breast cancer.| Susan G. Komen®
Alkermes’ alixorexton met primary and key secondary endpoints in a phase 2 trial for narcolepsy type 1, showing dose-dependent improvements.| Sleep Review
From St John’s wort to vitamin D, the range of over-the-counter supplements for mental health support and wellbeing continues to expand at a rate faster than scientists can validate their efficacy. Now, a new metastudy has assessed 64 different products reviewed in hundreds of studies to shed light…| New Atlas
Nektar Therapeutics stock skyrocketed 287% after rezpegaldesleukin hit all endpoints in atopic dermatitis trials, but ongoing litigation with Lilly could complicate matters.| Drug Discovery and Development
Memory loss in dementia presents challenges but clinical trials are paving the way for new treatment options that slows cognitive decline.| Princeton Medical Institute
Dupixent (dupilumab) has been approved by the FDA for the treatment of adult patients with bullous pemphigoid.| Drug Discovery and Development
The phase 4 EVEREST study showed that Dupixent demonstrated superiority over Xolair in adults with chronic rhinosinusitis.| Drug Discovery and Development
The FDA has approved zoliflodacin for the treatment of uncomplicated gonorrhea in adults and pediatric patients 12 years and older.| Drug Discovery and Development
The FDA has approved ENFLONSIA for the prevention of RSV lower respiratory tract disease in infants and newborns.| Drug Discovery and Development
This post is the latest in my series of “Wow! How? Health” stories, also shared on LinkedIn if you want to follow the conversation on that platform. When Michael Katz was diagnosed with multiple myeloma, he was fortunate to connect with someone who had recently completed treatment, the “just-in-time someone-like-me” that could guide him. He vowed to do the […]| Susannah Fox
Just over three-quarters of patients receiving Sanofi and Regeneron’s Dupixent achieved at least a 75% improvement in disease severity.| Drug Discovery and Development
Labcorp rolls out new NGS panels, HRD testing, and a Leica-Proscia digital pathology platform to accelerate biomarker screening.| Drug Discovery and Development
Explore the differences between Risk-Based Monitoring (RBM) and 100% Source Data Verification (SDV) for clinical trials| dicentra
May 02, 2005 Original Source: https://www.democracynow.org/2005/5/2/hundreds_of_hiv_foster_children_in| Message to Germany | Alliance for Human Research Protection
This month we feature clinical trials for colorectal cancer patients with minimal residual disease (MRD) after curative-intent treatment. MRD| Fight CRC
A three-year study has found robust evidence that one particular vaccine for respiratory syncytial virus (RSV) offers older adults long-term protection against the infection, even if efficacy wanes from season to season. Despite this, just a single dose cut serious illness by nearly two thirds, and…| New Atlas
Learn what a Clinical Research Feasibility Assessment (CRFA) is and how it helps sponsors plan, evaluate, and de-risk clinical trials.| dicentra
The primary objective of ERASur is to answer this question – Do patients with limited metastatic colorectal cancer live longer if| Fight CRC
The trial will test a novel UF-developed mRNA lipid nanoparticle (RNA-LP) in two pediatric cancers.| cancer.ufl.edu
A long-term human trial has found that a discontinued drug halved the presentation of early-onset Alzheimer's disease in people with a genetic predisposition to the devastating condition. Right now, symptoms are almost 100% likely to develop in patients between the ages of 30 and 65.| New Atlas
We learned much more about the role of circulating tumor DNA (ctDNA) tests in treating colorectal cancer at this meeting. I’m looking forward| Fight CRC
Advances in ADHD treatment are rapidly evolving, thanks to groundbreaking clinical trials that are uncovering more personalized and effective approaches. From innovative medications with fewer side effects to digital therapies and neurofeedback, these developments are opening up new possibilities for managing ADHD. Here’s how clinical trials are leading the way in shaping the future of … Current Advances in ADHD Treatment: How Clinical Trials Are Leading the Way Read More »| Princeton Medical Institute
Breast cancer treatment isn’t one-size-fits-all. Personalized care is tailored to you. Learn more about tailored plans and treatment.| Susan G. Komen®
Update 2025-02-07: This article is now available on OSF Preprints Update 2025-01-31: A French translation of this article is available here CORRELATION has published a new report entitled “Op…| CORRELATION
Alzheimer’s and dementia are complex, progressive conditions that impact millions of individuals and their families around the world. In the pursuit of effective treatments, clinical trials play an essential role, driving advancements in care, expanding treatment options, and offering hope to those affected. Through rigorous testing and research, clinical trials not only pave the way … The Role of Clinical Trials in Advancing Alzheimer’s and Dementia Care Read More »| Princeton Medical Institute
Two ALS centers launched an initiative to expand access to clinical trials and accelerate improvements in ALS research.| ALS News Today
Tetra Therapeutics has amended the protocols of two ongoing clinical trials testing zatolmilast to improve access for fragile X patients.| Fragile X News Today
Ever wondered how much you could earn by participating in a psychedelic clinical trial? Let's break down the potential earnings| HealingMaps
Kristy Phillips, founder and CEO of Clean Habits, is bringing a natural cleaning solution to United States homes and farms.| InnovationMap
Message from the Director Dear Friends of UCI MIND, Please enjoy the latest issue of MIND Matters from UCI MIND. In this Spring issue, we highlight a number of exciting updates about the impact UCI MIND investigators are having in the field. On the cover, post-doctoral fellow Dr. Claire Butler highlights progress made by the collaborative MODEL-AD group, including a publication she led. Another post-doctoral fellow, Dr. Jessica Noche, highlights an exciting collaboration in which UCI MIND ...| UCI MIND
As result of a commentary we wrote, Jama Psychiatry recently published a correction of a serious error in a 2023 paper on treating bipolar depression with psilocybin (together with Ioana Cristea and Florian Naudet). This correction included correcting the title of the paper itself. In this blog, I’ll very briefly discuss the core issue in... Read more »| Eiko Fried
A 2022 study on psilocybin has received a lot of criticism by the scientific community, but authors or journal have not corrected the record.| Eiko Fried
In a new systematic review, we compare 388 depression outcomes from 450 clinical trials to see which perform best.| Eiko Fried
I recently noticed that the Pfizer immunobridging trials, presumably set up to demonstrate that their COVID-19 vaccines elicit the same antibody response in children as was seen in 16-25 year olds, for whom efficacy has previously been demonstrated, have a strange criteria for “success”. GMT: geometric mean titer. This is a measure of the antibody titers. We use the geometric mean because this data is quite skewed (it is also why you typically see it plotted on the log scale). For those o...|
Message from the Director Dear Friends of UCI MIND, Happy New Year! We hope that 2024 is off to a positive start for you. As we embark upon a new year, UCI MIND and the field of Alzheimer’s disease and related dementias (ADRD) research are abuzz with excitement about progress made and opportunities to further advance our field. At the end of 2023, we held our annual signature fundraising event, the December to Remember Gala. We honored Lauren Miller Rogen and Seth Rogen, the founders of H...| UCI MIND
Studies claim psychedelics provide effective treatments against depression. Here I show you why this is not the case.| Eiko Fried
