Biotin is a very commonly used label for oligonucleotides, thanks to its high affinity for streptavidin. This property makes it ideal for a wide range of experiments, and in this ‘Know Your Oligo Mod’ blog post we’ll explore some of the options available for biotin tags and their uses. Streptavidin is a bacterial protein that avidly binds biotin, an essential vitamin for many organisms. With a dissociation constant about 10-15 M, this is one of the strongest non-covalent interactions be...| The BiosearchTech Blog
Long overlooked, circular RNAs are now recognized for their roles in gene regulation and disease. Learn how RNase R and circRNAs support the development of diagnostic biomarkers.| blog.biosearchtech.com
In April 2025, the MIQE guidelines for quantitative real-time PCR (qPCR) were updated for the first time since their initial release in 2009. This latest publication addresses the many advances in qPCR methods since then.| The BiosearchTech Blog
Understand the trade-offs of multiplex qPCR. What challenges do you need consider to achieve more efficient and cost-effective molecular diagnostics?| blog.biosearchtech.com
Understand the trade-offs of multiplex qPCR. What challenges do you need consider to achieve more efficient and cost-effective molecular diagnostics?| blog.biosearchtech.com
Discover the key considerations for designing and producing successful mRNA therapeutics. Learn about the manufacturing process, mRNA design, and purity testing to ensure scalable success in healthcare.| blog.biosearchtech.com