Results from a 2023 randomized, double-blind, placebo-controlled study revealed compelling findings on the impact of pomegranate (Punica granatum) extract on skin health, particularly through the gut-skin axis. Twenty-eight healthy adults aged 25–55 were administered either 75 mg of punicalagin, a potent polyphenol found in pomegranate (PE), or a placebo for four weeks. One of the most remarkable outcomes of PE supplementation was a significant increase in circulating levels of urolithin A ...
