Osteoarthritis (OA) is the most common disease of joints, afflicting millions of people all over the globe, but still none of the compound(s) discovered that inhibit the progressive degradation of the joints. In recent years, I with colleagues investigated some novel therapeutic targets at molecular levels,[7-9] which might be useful for drug designers for OA patients. In addition, my colleagues and I also have successfully tested the therapeutic potential of several natural dietary products ...