Recent studies on paleogenomics have reported some Paleolithic and Neolithic genomes that have provided new insights into the human population history in East and Northeast Asia. However, there remain some cases where more recent migration events ...| pmc.ncbi.nlm.nih.gov
Diabetes is a significant global health concern, highlighting the critical role of dietary strategies in its management and prevention. Artificial sweeteners (ASs), due to their capacity to provide sweetness without contributing to caloric intake, ...| pmc.ncbi.nlm.nih.gov
Psychedelics are a broad class of drugs defined by their ability to induce an altered state of consciousness1,2. These drugs have been used for millennia in both spiritual and medicinal contexts, and a number of recent clinical successes have ...| pmc.ncbi.nlm.nih.gov
The presence of new neurons in the adult hippocampus indicates that this structure incorporates new neurons into its circuitry and uses them for some function related to learning and/or related thought processes. Their generation depends on a ...| pmc.ncbi.nlm.nih.gov
Decades of research have shown that childhood experiences interact with our genetics to change the structure and function of the brain. Within the range of normal experiences, this system enables the brain to be modified during development to adapt ...| pmc.ncbi.nlm.nih.gov
Recovery is described as a process that is in contrast to the process whereby the psychological stress response increases. Recovery experiences refer to specific experiences that promote recovery and represent psychological attributes including ...| pmc.ncbi.nlm.nih.gov
Black pepper (Piper nigrum L.) has been employed in medicine (epilepsy, headaches, and diabetes), where its effects are mainly attributed to a nitrogen alkaloid called piperidine (1-(1-[1,3-benzodioxol-5-yl]-1-oxo-2,4 pentenyl) piperidine). Piperine ...| pmc.ncbi.nlm.nih.gov
Ashwagandha (Withania somnifera) is a herb commonly used in Ayurvedic medicine to promote youthful vigor, enhance muscle strength and endurance, and improve overall health. In this 16-week, randomized, double-blind, placebo-controlled, crossover ...| pmc.ncbi.nlm.nih.gov
Type 2 diabetes is often associated with obesity, dyslipidemia, and cardiovascular anomalies and is a major health problem approaching global epidemic proportions. Insulin resistance, a prediabetic condition, precedes the onset of frank type 2 ...| pmc.ncbi.nlm.nih.gov
The incidence of thyroid cancer is four to five times higher in women than in men, suggesting a role for estrogen (E2) in the pathogenesis of thyroid proliferative disease (TPD) that comprises cancer and goiter. The objective of this study was to ...| pmc.ncbi.nlm.nih.gov
Approaches to youth development that enhance connectedness and opportunities for young people are key to adolescent health and wellbeing argue Robert Blum and colleagues| pmc.ncbi.nlm.nih.gov
Rostral prefrontal cortex (RPFC) supports self-generated, abstract thought processing. Flexibly attending towards and processing abstract thoughts develop in adolescence. RPFC activation becomes more specific to relational integration during ...| pmc.ncbi.nlm.nih.gov
Hospice and palliative care help patients with cancer to engage in discussions about their goals related to their care and to live more comfortably at their end of life. Advance care planning (ACP) involves making decisions about patients’ future ...| pmc.ncbi.nlm.nih.gov
Physicians’ and patients’ decision-making process between bone-patellar tendon-bone (BTB) versus hamstring autografts for anterior cruciate ligament (ACL) reconstruction (ACLR) may be influenced by a variety of factors in the young, active athlete. ...| pmc.ncbi.nlm.nih.gov
In the dynamic field of organizational behavior, comprehending the determinants of employee engagement, burnout, and job satisfaction is pivotal. This research investigates the influence of various workplace factors, such as recognition, fairness, ...| pmc.ncbi.nlm.nih.gov
Despite their increasing ubiquity in people's lives and incredible advantages in instantly interacting with others, social media's impact on subjective well-being is a source of concern worldwide and calls for up-to-date investigations of the role ...| pmc.ncbi.nlm.nih.gov
Involvement of dopamine neurotransmission in human emotional processing is unclear but animal studies have indicated that it is critical for processing of fear response. In this experiment we examined dopaminergic involvement in the processing of ...| pmc.ncbi.nlm.nih.gov
Several clinical trials have found that consuming more protein than the recommended dietary allowance not only reduces body weight (BW), but also enhances body composition by decreasing fat mass while preserving fat-free mass (FFM) in both ...| pmc.ncbi.nlm.nih.gov
Dry socket is one of the most common complications that develops after the extraction of a permanent tooth, and its prevention is more effective than its treatment. Analyze the efficacy of different methods used in preventing dry socket in order to ...| pmc.ncbi.nlm.nih.gov
Aim: The purpose of this study was to determine clinical success rate of single visit verses multiple visit root canal treatment in cariously exposed vital primary molars. Material& methods: 40 children in age group of 4 to 7 years were divided ...| pmc.ncbi.nlm.nih.gov
Boredom is a unique human emotion. Understanding its causes and consequences and how people learn to cope with it to develop new ideas and inspiration could help to alleviate its negative effects. Subject terms: Evolution & Ecology, Neuroscience| pmc.ncbi.nlm.nih.gov
The 1918 Spanish flu virus has claimed more than 50 million lives. However, the mechanism of its high pathogenicity remains elusive; and the origin of the virus is controversial. The matrix (M) segment regulates the replication of influenza A virus, ...| pmc.ncbi.nlm.nih.gov
This study examined the impact of workplace environment on employee task performance under the mediating role of employee commitment and achievement-striving ability. For this purpose, data were collected from the academic staff under a ...| pmc.ncbi.nlm.nih.gov
This article provides practical perspective and guidance for transitioning from in‐person to virtual learning. Student engagement is emphasized through providing synchronous and highly interactive virtual learning sessions. This approach not only ...| pmc.ncbi.nlm.nih.gov
Tirzepatide is a promising drug with dual-acting glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor activation that has revolutionized the treatment of type 2 diabetes mellitus (T2DM) as an adjunct to ...| pmc.ncbi.nlm.nih.gov
Obesity is a chronic, relapsing disease associated with multiple complications and a substantial morbidity, mortality and health care burden. Pharmacological treatments for obesity provide a valuable adjunct to lifestyle intervention, which often ...| pmc.ncbi.nlm.nih.gov
Alcoholic hallucinosis is a rare complication of chronic alcohol abuse characterized by predominantly auditory hallucinations that occur either during or after a period of heavy alcohol consumption. Bleuler (1916) termed the condition as alcohol ...| pmc.ncbi.nlm.nih.gov
Disease processes or events that accompany acute alcohol withdrawal (AW) can cause significant illness and death. Some patients experience seizures, which may increase in severity with subsequent AW episodes. Another potential AW complication is ...| pmc.ncbi.nlm.nih.gov
Relapse is a highly prevalent phenomenon in addiction. This paper examines the new research on identifying biological factors that contribute to addiction relapse risk. Prospective studies examining relapse risk are reviewed, and clinical, ...| pmc.ncbi.nlm.nih.gov
Although social support is commonly investigated in the context of substance recovery, researchers have widely neglected its multilevel nature, thus limiting what we know about its measurement across levels of observation. The current study used ...| pmc.ncbi.nlm.nih.gov
Artificial sweeteners are widely-used sugar substitutes, but little is known about their long-term effects on cardiometabolic disease risks. Here, we examined the commonly-used sugar substitute erythritol and atherothrombotic disease risk. In ...| pmc.ncbi.nlm.nih.gov
To estimate the effect of the first full year of the ACA Medicaid expansion on hospital provision of uncompensated care, with special attention paid to hospitals that treat a disproportionate share of low‐income patients. Data from a balanced panel ...| pmc.ncbi.nlm.nih.gov
The Patient Protection and Affordable Care Act (ACA) expands access to health insurance in the United States, and, to date, an estimated 20 million previously uninsured individuals have gained coverage. Understanding the law’s impact on coverage, ...| pmc.ncbi.nlm.nih.gov
Partial hospitalization programs represent a midpoint along the treatment intensity continuum between an inpatient and an outpatient service. Partial hospitalization programs can be used in place of an inpatient unit for patients who need crisis ...| pmc.ncbi.nlm.nih.gov
Breastfeeding is acknowledged as optimal infant nutrition, yet despite high initiation rates, early cessation remains common. To understand why, we asked mothers in Western Canada how they felt about their breastfeeding experience. A total of 191 ...| pmc.ncbi.nlm.nih.gov
“Sundowning syndrome” refers to the evening decline in mental state among cognitively impaired patients. This phenomenon is well known, but it is not entirely understood. Its prevalence ranges from 1.6% to 66% of patients with dementia. Development ...| pmc.ncbi.nlm.nih.gov
In 2016, New York City (NYC) began enforcing a sodium warning regulation at chain restaurants, requiring placement of an icon next to any menu item containing ≥2,300 mg sodium. As menu labeling may improve menu nutritional composition, we ...| pmc.ncbi.nlm.nih.gov
In 2016, New York City (NYC) began enforcing a sodium warning regulation at chain restaurants, requiring placement of an icon next to any menu item containing ≥2,300 mg sodium. As shifts in consumer purchases are a potential outcome of menu ...| pmc.ncbi.nlm.nih.gov
The authors examined the mediating role of perceived organizational support in the relationship between mentoring support received and work attitudes. Perceived organizational support partly mediated the relationship between specific types of ...| pmc.ncbi.nlm.nih.gov
This study marks the 50th anniversary of NAPCRG (formerly the North American Primary Care Research Group) by examining social connections among members. This descriptive social network analysis was conducted via the Program to Analyze, Record, and ...| pmc.ncbi.nlm.nih.gov
Low back pain and depression have been globally recognized as key public health problems and they are considered co-morbid conditions. This study explores both cross-sectional and longitudinal comorbid associations between back pain and major ...| pmc.ncbi.nlm.nih.gov
The hypothalamic-pituitary-ovarian (HPO) axis is a tightly regulated system controlling female reproduction. HPO axis dysfunction leading to ovulation disorders can be classified into three categories defined by the World Health Organization (WHO). ...| pmc.ncbi.nlm.nih.gov
To find out whether the vomeronasal organ (VNO) can be identified in the nose as a mucosal pit in the anterior nasal septum, to elucidate its function in man and to determine whether it is important to preserve the VNO during septal surgery. ...| pmc.ncbi.nlm.nih.gov
This study explores the significant role chiropractic care can play in the sports industry, with a focus on countries like China and Hong Kong. As a vital component of sports medicine, chiropractic care can enhance athletic performance, health, and ...| pmc.ncbi.nlm.nih.gov
There have been mixed findings of clinicians’ perceptions of Electronic Health Record (EHR). This study aims to explore the lived experiences of clinicians, to assess the role of EHR in improving the quality and safety of healthcare. A qualitative ...| pmc.ncbi.nlm.nih.gov
Billions of public dollars are spent each year on biologic disease-modifying anti-rheumatic drugs (bDMARDs), but the drivers of recent increases in bDMARD spending are unclear. We characterized changes in total spending and unit-prices for bDMARDs ...| pmc.ncbi.nlm.nih.gov
Cataract Blindness| pmc.ncbi.nlm.nih.gov
The term “predictive brain” depicts one of the most relevant concepts in cognitive neuroscience which emphasizes the importance of “looking into the future”, namely prediction, preparation, anticipation, prospection or expectations in various ...| pmc.ncbi.nlm.nih.gov
Objective: Mental imagery involves forming internal sensory representations, while osteoarthritis is a degenerative joint disease characterized by cartilage loss. This study explores how mental imagery can modulate pain perception and enhance visual ...| pmc.ncbi.nlm.nih.gov
The revolution in information availability and the advances in novel interaction technologies have ushered in two major shifts that call into question the traditional assumptions of buyer–seller interactions. First, buyer–seller information ...| pmc.ncbi.nlm.nih.gov
Social media, integral to contemporary life, offers significant connectivity and entertainment benefits. However, its pervasive use has given rise to social media addiction, particularly among teenagers, characterized by excessive screen time, ...| pmc.ncbi.nlm.nih.gov
Given the prevalence of transfer activity, education stakeholders must understand how transfer may be associated with student outcomes. Such knowledge is critical, as the COVID-19 pandemic and economic downturn have impacted college enrollment and ...| pmc.ncbi.nlm.nih.gov
Natural language processing (NLP) tasks can be addressed with several deep learning architectures, and many different approaches have proven to be efficient. This study aims to briefly summarize the use cases for NLP tasks along with the main ...| pmc.ncbi.nlm.nih.gov
Negotiation is a consequential activity that can exacerbate power differentials, especially for women. While traditional contexts can prime stereotypical gender roles and promote conditions that lead to performance differences, these can be ...| pmc.ncbi.nlm.nih.gov
Adaptogens were initially defined as substances that enhance the “state of non-specific resistance” in stress, a physiological condition that is linked with various disorders of the neuroendocrine-immune system. Studies on animals and isolated ...| pmc.ncbi.nlm.nih.gov
Objective: To describe a young patient with scorpion sting (SS) with typical lesions of urticaria besides the local SS clinical picture. Materials and methods: A systematic screening of articles dating from 1966 to 2021 was conducted in the main ...| pmc.ncbi.nlm.nih.gov
Excessive visceral adipose tissue appears to trigger a cascade of metabolic disturbances that seem to coexist with ectopic fat storage in muscle, liver, heart and the ß-cell. Therefore, the reduction of visceral adipose tissue potentially plays a ...| pmc.ncbi.nlm.nih.gov
There are variable reports of risk of concordance for progression to islet autoantibodies and type 1 diabetes in identical twins after one twin is diagnosed. We examined development of positive autoantibodies and type 1 diabetes and the effects of ...| pmc.ncbi.nlm.nih.gov
Transgender youth, including adolescent and young adult transgender women assigned a male sex at birth who identify as girls, women, transgender women, transfemale, male-to-female, or another diverse transfeminine gender identity, represent a ...| pmc.ncbi.nlm.nih.gov
1Centro de Administração e Políticas Públicas, Instituto Superior de Ciências Sociais e Políticas, Universidade de Lisboa, Lisbon, Portugal| pmc.ncbi.nlm.nih.gov
The use of telehealth steadily increases as it has become a viable modality to patient care. Early adopters attempt to use telehealth to deliver high-quality care. Patient satisfaction is a key indicator of how well the telemedicine modality met ...| pmc.ncbi.nlm.nih.gov
This study examined the gut microbiota of 175 Beagle dogs living in a colony across three age groups Junior (43 dogs), Adult (58 dogs), and Senior (74 dogs) and assessed the impact of osteoarthritis on microbial composition. Shannon and Chao1 alpha ...| pmc.ncbi.nlm.nih.gov
Nootropics, also known as “smart drugs” are a diverse group of medicinal substances whose action improves human thinking, learning, and memory, especially in cases where these functions are impaired. This review provides an up-to-date overview of ...| pmc.ncbi.nlm.nih.gov
Age-related cognitive decline has been suggested to result from an increase in the brain neuron loss, which is attributable to continued derangement of the brain’s oxidant/antioxidant balance. Increased oxidative stress and a concomitant decrease in ...| pmc.ncbi.nlm.nih.gov
Nootropics or smart drugs are well-known compounds or supplements that enhance the cognitive performance. They work by increasing the mental function such as memory, creativity, motivation, and attention. Recent researches were focused on ...| pmc.ncbi.nlm.nih.gov
The association between blood pressure (BP) and dementia in older adults remains unclear, prompting this study to investigate the relationship between various BP indicators and dementia in this population. A cross-sectional survey was conducted in ...| pmc.ncbi.nlm.nih.gov
Osteopathic manipulative medicine (OMM) is an emerging practice in the healthcare field with increasing popularity and evidence-based therapy. Osteopathic manipulative treatments (OMT) include hands-on manipulations of different body structures to ...| pmc.ncbi.nlm.nih.gov
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The global mental health crisis underscores the need for accessible, effective interventions. Chatbots based on generative artificial intelligence (AI), like ChatGPT, are emerging as novel solutions, but research on real-life usage is limited. We ...| pmc.ncbi.nlm.nih.gov
Background: Fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) are an heterogeneous group of compounds that can be poorly digested and may have a range of effects on gastrointestinal processes. FODMAPs are found in a ...| pmc.ncbi.nlm.nih.gov
A dose non-inferiority study comparing 100 mg, 300 mg and 600 mg of aspirin for cancer prevention among Lynch Syndrome carriers is underway (Colorectal Adenoma/Carcinoma Prevention Programme trial 3, CaPP3). To guide implementation of the findings, ...| pmc.ncbi.nlm.nih.gov
Regular hospital visits can be expensive, particularly in rural areas, due to travel costs. In the era of the Covid-19 Pandemic, where physical interaction becomes risky, people prefer telemedicine. Fortunately, medical visits can be reduced when ...| pmc.ncbi.nlm.nih.gov
Depression is a common disorder linked with high levels of chronicity, psycho-social and physical problems, and suicide. Here, we assessed the antidepressant effects of the hydromethanolic extract of Taraxacum officinale and investigated the ...| pmc.ncbi.nlm.nih.gov
Dandelion extracts have been studied extensively in recent years for its anti-depressant and anti-inflammatory activity. Recent work from our lab, with in-vitro systems, shows the anti-cancer potential of an aqueous dandelion root extract (DRE) in ...| pmc.ncbi.nlm.nih.gov
The skeletal muscle is the largest organ in the body, by mass. It is also the regulator of glucose homeostasis, responsible for 80% of postprandial glucose uptake from the circulation. Skeletal muscle is essential for metabolism, both for its role ...| pmc.ncbi.nlm.nih.gov
The aim of this study was to compare the effects of resistance training to muscle failure (RT-F) and non-failure (RT-NF) on muscle mass, strength and activation of trained individuals. We also compared the effects of these protocols on muscle ...| pmc.ncbi.nlm.nih.gov
This review article focuses on the changes that occur in muscle with age, specifically the involuntary loss of muscle mass, strength and function, termed sarcopenia. Particular emphasis is given to the metabolic alterations that characterize ...| pmc.ncbi.nlm.nih.gov
Impairment of mental health is the most important risk factor for female sexual dysfunction. Women living with psychiatric illness, despite their frequent sexual difficulties, consider sexuality to be an important aspect of their quality of life. ...| pmc.ncbi.nlm.nih.gov
Transgender people report discomfort with their birth sex and a strong identification with the opposite sex. The current study was designed to shed further light on the question of whether the brains of transgender people resemble their birth sex or ...| pmc.ncbi.nlm.nih.gov
Artificial intelligence in the workplace is becoming increasingly common. These tools are sometimes used to aid users in performing their task, for example, when an artificial intelligence tool assists a radiologist in their search for abnormalities ...| pmc.ncbi.nlm.nih.gov
To meet increasing demand, healthcare systems may leverage shorter appointment lengths to compensate for a limited supply of primary care providers (PCPs). Limiting the time spent with patients when evaluating acute health needs may adversely affect ...| pmc.ncbi.nlm.nih.gov
What are the administrative costs associated with billing and insurance-related activities at an academic health care system with a certified electronic health record system? In a time-driven activity-based costing study of personnel and overhead ...| pmc.ncbi.nlm.nih.gov
Interest in the study of emotions in education has grown in recent years. Some of our modern challenges, such as constantly adapting to new scenarios or the need for team work have justified the introduction of emotional competence into educational ...| pmc.ncbi.nlm.nih.gov
Preparing to download ...| pmc.ncbi.nlm.nih.gov
The carcinogenic risk from space radiation has always been a health risk issue of great concern during space exploration. In recent years, a large number of cellular and animal experiments have demonstrated that space radiation, composed of ...| pmc.ncbi.nlm.nih.gov
In this descriptive study, we aimed to identify factors related to emergency room nurses’ disaster triage ability. A total of 166 nurses who worked for emergency departments of general hospitals completed a structured questionnaire consisting of the ...| pmc.ncbi.nlm.nih.gov
This study extends probiotic cleaning research to a built environment. Through an eight-month cleaning trial, we compared the effect of three cleaning products (disinfectant, plain soap, and a probiotic cleaner containing a patented Bacillus spore ...| pmc.ncbi.nlm.nih.gov
Research suggests that body image affects sexual functioning, but the relationship between specific types of body image (evaluative, affective, and behavioral) and domains of sexual functioning (desire, arousal, and orgasm) has not been ...| pmc.ncbi.nlm.nih.gov
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Humans often make decisions in stressful situations, for example when the stakes are high and the potential consequences severe, or when the clock is ticking and the task demand is overwhelming. In response, a whole train of biological responses to ...| pmc.ncbi.nlm.nih.gov
Endocrine-disrupting chemicals (EDCs) are known contributors to breast cancer development. Exposures to EDCs commonly occur through food packaging, cookware, fabrics, and personal care products, as well as external environmental sources. Increasing ...| pmc.ncbi.nlm.nih.gov
Although endocrine therapy (ET) is the preferred option for hormone receptor-positive HER2-negative metastatic breast cancer (HR+/HER2– MBC), chemotherapy (CT) is still commonly used. The objective of this real-world study was to present the actual ...| pmc.ncbi.nlm.nih.gov
Organic light-emitting diodes (OLEDs) emit less blue light than traditional light-emitting diodes (LEDs), and we previously found that early-night OLED light exposure (LE) delays the melatonin phase by less than LED at a color temperature of 4,000 ...| pmc.ncbi.nlm.nih.gov
While research identifies a growing list of risk factors for anxiety and depression, it is equally important to identify potential protective factors that may prevent or reduce vulnerability to developing internalizing psychopathology. We ...| pmc.ncbi.nlm.nih.gov
Africa is the source of all modern humans, but characterization of genetic variation and of relationships among populations across the continent has been enigmatic. We studied 121 African populations, four African American populations, and 60 ...| pmc.ncbi.nlm.nih.gov
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In spite of copious literature investigating body dissatisfaction and its correlates in adolescents and young adult women, exploration of body image disturbances in adult women remains an underrepresented domain in the literature. Yet, there are ...| pmc.ncbi.nlm.nih.gov
Tanzania had experienced hundreds of cases of aflatoxicosis in the districts of Kiteto, Chemba, and Kondoa for the three consecutive years since 2016. Cases may end up with liver cancer. Aflatoxin-induced liver cancer had resulted in the demise of ...| pmc.ncbi.nlm.nih.gov
Police officers have one of the poorest cardiovascular disease (CVD) health profiles of any occupation. The goal of this study was to determine if police officers in the Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) Study (between 2004 ...| pmc.ncbi.nlm.nih.gov
In recent decades, hormonal contraceptives (HC) has made a difference in the control of female fertility, taking an unequivocal role in improving contraceptive efficacy. Some side effects of hormonal treatments have been carefully studied. However, ...| pmc.ncbi.nlm.nih.gov