The human body is not able to excrete excess amounts of iron actively.[1] Iron is absorbed from the small intestine each day and balanced by losses through sweating, menstruation, shedding of hair and skin cells, and the rapid turnover and excretion of erythrocytes.[2] The average daily absorption and secretion is 1 mg. Patients receiving transfusions for non-iron deficiency anemias are at risk for transfusion-related iron overload. The following is a list of transfusion-dependent conditions: