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From:
blog.biosearchtech.com
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Nucleic Acid Therapeutics Toolbox: Givosiran, the first liver-targeted siRNA drug
https://blog.biosearchtech.com/nucleic-acid-therapeutics-toolbox-givosiran
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nucleic acid therapeutics
This blog post reviews the chemical modifications that made givosiran an effective treatment in vivo and set the stage for the siRNA drugs that followed.
