To assess submitted content, the JCI and JCI Insight rely primarily on academic editors who are active researchers themselves. With broad scientific knowledge, our editors scrutinize the rigor, quality, and potential impact of manuscripts both before and after the peer review process, relying on their ongoing experiences as active investigators. At the JCI, about 25% of submitted articles are judged to be of a quality and impact deserving of more detailed external peer review. For this, we de...