BACKGROUND: Conditions like fibrosis, rheumatoid arthritis or cancer, once seen as distinct diseases, are now recognized to share strikingly common pathogenic mechanisms. The key to this convergence lies in the fibroblast, a pivotal driver of disease progression, tissue injury and chronicity. Despite this central pathogenic role and growing recognition as a therapeutic target, effective treatments targeting fibroblasts remain elusive, leaving a critical gap in disease intervention. METHODS: H...
