Road transport is a prominent source of carbon emissions. However, fine-grained regional estimations on road carbon dioxide (CO2) emissions are still lacking. This study estimates road CO2 emissions in Guangdong Province, China, at high spatiotemporal resolution, with a bottom-up framework leveraging massive vehicle trajectory data. We unveil the spatiotemporal pattern of regional road CO2 emissions and highlight the contrasts among cities. The Greater Bay Area (GBA) is found to produce 76 % ...