Mayaro virus (MAYV) is an alphavirus transmitted by mosquito vectors. Among the three MAYV genotypes (D, L, and N), genotype D has the broadest geographical distribution in Latin America and the Caribbean. The virus can be transmitted by the Aedes, Anopheles, and Haemagogus mosquitoes. To explore the potential expansion of MAYV across the Atlantic Ocean, we compared MAYV (D) infection kinetics in Floridian Aedes aegypti with New World (Anopheles albimanus) and Old World (Anopheles gambiae) an...| MDPI
We study the concepts of residence time vs. adjustment time time for carbon dioxide in the atmosphere. The system is analyzed with a two-box first-order model. Using this model, we reach three important conclusions: (1) The adjustment time is never larger than the residence time and can, thus, not be longer than about 5 years. (2) The idea of the atmosphere being stable at 280 ppm in pre-industrial times is untenable. (3) Nearly 90% of all anthropogenic carbon dioxide has already been removed...| MDPI
A novel strategy for improving wet resistance and bonding properties of starch-based adhesives using enzymatically polymerized lignosulfonates and carboxylic acids as additives was developed. Therefore, lignosulfonates were polymerized by laccase to a molecular weight of 750 kDa. Incorporation of low concentrations (up to 1% of the starch weight) of 1,2,3,4-butanetetracarboxylic acid (BTCA) led to further improvement on the properties of the adhesives, while addition of greater amounts of BTC...| MDPI
Gait is commonly defined as the movement pattern of the limbs over a hard substrate, and it serves as a source of identification information for various computer-vision and image-understanding techniques. A variety of parameters, such as human clothing, angle shift, walking style, occlusion, and so on, have a significant impact on gait-recognition systems, making the scene quite complex to handle. In this article, we propose a system that effectively handles problems associated with viewing a...| MDPI
Anthropomorphism is a natural tendency in humans, but it is also influenced by many characteristics of the observer (the human) and the observed entity (here, the animal species). This study asked participants to complete an online questionnaire about three videos showing epimeletic behaviours in three animal species. In the videos, an individual (a sparrow, an elephant and a macaque, respectively) displayed behaviours towards an inanimate conspecific that suddenly regained consciousness at t...| MDPI
This review explores the integration of Artificial Intelligence (AI) with Sentinel-2 satellite data in the context of precision agriculture, specifically for crop yield estimation. The rapid advancements in remote sensing technology, particularly through Sentinel-2’s high-resolution multispectral imagery, have transformed agricultural monitoring by providing critical data on plant health, soil moisture, and growth patterns. By leveraging Vegetation Indices (VIs) derived from these images, A...| MDPI
In the pursuit of longevity and healthspan, we are challenged with first overcoming chronic diseases of ageing: cardiovascular disease, hypertension, cancer, dementias, type 2 diabetes mellitus. These are hyperinsulinaemia diseases presented in different tissue types. Hyperinsulinaemia reduces endogenous antioxidants, via increased consumption and reduced synthesis. Hyperinsulinaemia enforces glucose fuelling, consuming 4 NAD+ to produce 2 acetyl moieties; beta-oxidation, ketolysis and acetoa...| MDPI
The non-invasiveness of photoplethysmographic (PPG) acquisition systems, together with their cost-effectiveness and easiness of connection with IoT technologies, is opening up to the possibility of their widespread use. For this reason, the study of the reliability of PPG and pulse rate variability (PRV) signal quality has become of great scientific, technological, and commercial interest. In this field, sensor location has been demonstrated to play a crucial role. The goal of this study was ...| MDPI
Solar photovoltaic (PV) generation technology stands out as a scalable and cost-effective solution to enable the transition toward decarbonization. However, PV solar output, beyond the daily solar irradiance variability and unavailability during nights, is very sensitive to weather events like hurricanes. Hurricanes nucleate massive amounts of clouds around their centers, shading hundreds of kilometers in their path, reducing PV power output. This research proposes a spatiotemporal method, im...| MDPI
Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disorder characterized by insulin resistance and beta cell dysfunction, resulting in hyperglycemia. Olive oil, a cornerstone of the Mediterranean diet, has attracted considerable attention due to its potential health benefits, including reducing the risk of developing T2DM. This literature review aims to critically examine and synthesize existing research regarding the impact of olive oil on the expression of genes relevant to T2DM...| MDPI
Background/Objectives: Embryo selection in IVF is traditionally based on morphology, yet many high-quality embryos fail to implant. Preimplantation genetic testing for aneuploidy (PGT-A) using next-generation sequencing (NGS) has been proposed to improve selection by identifying euploid embryos. However, its effectiveness in women of advanced maternal age remains unclear due to limited randomized data. This pilot trial assessed the feasibility of a full-scale RCT comparing PGT-A to morphology...| MDPI
Ensuring sustainable food systems is an urgent global priority as populations grow and environmental pressures mount. Technological innovations such as genetic engineering (GE) and nanotechnology (nano) have been promoted as promising pathways for achieving greater sustainability in agriculture and food production. Yet, the sustainability of these technologies is not defined by technical performance alone; it hinges on how they are perceived by key stakeholders and how well they align with br...| MDPI
The influence of semi-hard (C1), hard (C2), and soft whey cheese (C3) immersed in extra virgin olive oil (EVOO) on its oxidative and hydrolytic parameters, fatty acids, and phenolic composition during two months of simultaneous storage was investigated. Accelerated hydrolytic and oxidative degradation was noted in EVOO stored with the immersed cheese compared to control oil. Oxidation indicator (K232), myristic (C 14:0), and trans-oleic fatty acid (C18:1t) exceeded the prescribed limit for th...| MDPI
The gut microbiota plays a key role in mental health, with growing evidence linking its composition to anxiety and depressive disorders. Research on this topic has expanded significantly in recent years. This review explores alterations in the gut microbiota of individuals with anxiety disorders and examines the potential therapeutic effects of probiotics. Background/Objectives: This review aims to analyze the alterations in gut microbiota composition in individuals with anxiety disorders and...| MDPI
The college and university presidency is one of the most coveted positions in academe. Due to the projected retirements of current Historically Black College and University (HBCU) presidents, the researchers interviewed 21 current presidents, institutional board members, and presidential search firm personnel to explore what current HBCU leadership identifies as important mentoring/mentee practices, mentoring/mentee opportunities, and professional advice for HBCU presidential aspirants to con...| MDPI
Bovine viral diarrhea virus (BVDV) is a globally significant pathogen affecting both domestic livestock and wildlife, including white-tailed deer (WTD; Odocoileus virginianus). While experimental infections have demonstrated WTD susceptibility to BVDV, natural infections and associated reproductive outcomes remain scarcely documented. Here, we report the first confirmed case of naturally occurring BVDV-1 infection associated with fetal mummification in farmed WTD in Florida.| Emerging Pathogens Institute » University of Florida
Mosquito blood meals provide a biological sample of host blood which can then be used in downstream applications including host–pathogen detection. We conducted DNA barcoding to identify the host species of blood meals from 4557 blood engorged mosquitoes collected in south central Florida, USA. We identified 314 blood meals from invasive wild pigs, 219 wild turkey blood meals, and 1046 white-tailed deer blood meals. From a subset of these host blood meals, we used molecular assays to detect...| MDPI
Oat is among the food crops and ancient grains cultivated and consumed worldwide. It is gaining in popularity owing to its nutritional composition and multifunctional benefits of select bioactive compounds. Beta-glucan is an important component of dietary fiber found in oat grains. It is the major active compound in oats with proven cholesterol-lowering and antidiabetic effects. Oats also provide substantial levels of other bioactive compounds such as phenolic acids, tocols, sterols, avenacos...| MDPI
Consumption of flavonoid-rich nutraceuticals has been associated with a reduction in coronary events. The present study analyzed the effects of cocoa flavonols on myocardial injury following acute coronary ischemia-reperfusion (I/R). A commercially available cocoa extract was identified by chromatographic mass spectrometry. Nineteen different phenolic compounds were identified and 250 mg of flavan-3-ols (procyanidin) were isolated in 1 g of extract. Oral administration of cocoa extract in inc...| MDPI
This research examines the potential economic rebirth of the Central Appalachian Region as persons from the southwestern and southeastern parts of the United States seek a safe and livable environment for their families and businesses. Central Appalachia is projected to be the largest habitable area in the continental United States by the year 2050. However, mined land remediation, water control efforts, and hydro-electric energy generation units will be required to support the incoming popul...| MDPI
The use of renewable biological resources, including biowaste, within a circular framework, is crucial for the transition to more sustainable production and consumption patterns. By means of life cycle assessment and life cycle costing methodologies, this study compares the environmental and economic performances of two disposal scenarios for coffee silverskin, the major waste from coffee roasting. The business-as-usual (BaU) scenario, currently applied in the Metropolitan City of Naples (Ita...| MDPI
This paper describes the development and testing of a classroom and complementary home-based intervention to build preschoolers’ spatial orientation skills, focusing on exploring implementation feasibility and initial child learning outcomes. Spatial orientation, one type of spatial thinking, involves understanding the relationship between spatial positions, using maps and models to represent and navigate through space, and using spatial vocabulary. Evidence continues to accumulate that gai...| MDPI
Machine learning and deep learning technologies are rapidly advancing the capabilities of sensing technologies, bringing about significant improvements in accuracy, sensitivity, and adaptability. These advancements are making a notable impact across a broad spectrum of fields, including industrial automation, robotics, biomedical engineering, and civil infrastructure monitoring. The core of this transformative shift lies in the integration of artificial intelligence (AI) with sensor technolog...| MDPI
Achieving the Paris Agreement’s 1.5 °C target requires a global-scale energy transition, reaching net-zero emissions by 2050. This transition demands not only a rapid expansion of renewable energy but also significant upfront energy investment, presenting potential trade-offs between near-term energy security and long-term sustainability. Assuming we cannot rely on as yet unproven negative emissions technology, reductions must be achieved directly, requiring fossil fuel phase-out, accelera...| MDPI
Caffeine (CAF), a prevalent psychoactive stimulant, is believed to potentially enhance cognitive ability. However, studies on the effects of various doses are limited and yield inconsistent results, particularly in female athletes. Therefore, we aimed to assess the association between three different dosages of CAF intake (low, moderate, and high) and cognitive skills in female athletes with low CAF consumption. This study had a randomized, crossover, double-blind design in which each athlete...| MDPI
In the realm of sustainable IoT and AI applications for the well-being of elderly individuals living alone in their homes, falls can have severe consequences. These consequences include post-fall complications and extended periods of immobility on the floor. Researchers have been exploring various techniques for fall detection over the past decade, and this study introduces an innovative Elder Fall Detection system that harnesses IoT and AI technologies. In our IoT configuration, we integrate...| MDPI
Excessive use of smartphones has been associated with a number of negative consequences for individuals. Some of these consequences relate to many symptoms of behavioral addiction. The present study aims to investigate whether participants with high levels of smartphone usage may have difficulty with their ability to wield the self-control that is needed to restrict smartphone usage compared to participants with lower levels of smartphone addiction. Specifically, we expect that people with hi...| MDPI
Purchasing through virtual market is different from the process that takes place in the traditional market. In this market, things are less tangible and more threatening. Therefore, trust becomes crucial and it is established in a different way. This study examined the effect of testimonials on the level of trust in e-commerce. It also examined the impact of product touch level and price on the effect of testimonials. Two mock e-commerce sites were used, one with testimonials and the other wi...| MDPI
Permafrost-affected tundra soils are large carbon (C) and nitrogen (N) reservoirs. However, N is largely bound in soil organic matter (SOM), and ecosystems generally have low N availability. Therefore, microbial induced N-cycling processes and N losses were considered negligible. Recent studies show that microbial N processing rates, inorganic N availability, and lateral N losses from thawing permafrost increase when vegetation cover is disturbed, resulting in reduced N uptake or increased N ...| MDPI
Permafrost-affected landscape soils are rich in organic matter and contain a high fraction of organic nitrogen, but much of this organic matter remains inaccessible due to nitrogen limitation. Microbial nitrification is a key process in the nitrogen cycle, controlling the availability of dissolved inorganic nitrogen (DIN) such as ammonium and nitrate. In this study, we investigate the microbial diversity of canonical nitrifiers and their potential nitrifying activity in the active layer of di...| MDPI
By incorporating elements such as storytelling, problem-solving, and rewards, serious games can appeal to varied users, making the learning process more experiential, engaging, and enjoyable. Gender stereotyping is a prevalent social problem that occurs to a greater or lesser extent in all countries and cultures around the world. However, it is more present in certain places like Latin American countries. This study presents the evaluation of Kiddo, a serious game to raise awareness about gen...| MDPI
Video games are recognized as significant tools and mediums to be used in civic participation in spatial planning and fostering local communities. As the phenomenon is widely recognized in papers presenting singular case studies and broader analyses in the field, selecting such serious games with certain characteristics remains unclear. The informed process of choosing games with particular properties regarding genesis, graphic style, genre, and complexity as the response for specified needs ...| MDPI
Breast cancer is a leading cause of cancer-related mortality worldwide, requiring efficient diagnostic tools for early detection and monitoring. Human epidermal growth factor receptor 2 (HER2) is a key biomarker for breast cancer classification, typically assessed using immunohistochemistry (IHC). However, IHC requires invasive biopsies and time-intensive laboratory procedures. In this study, we present a biosensor integrated with a reusable printed circuit board (PCB) and functionalized gluc...| MDPI
This study presents a seasonal synoptic climatology of cut-off lows (COLs) that produced extreme precipitation in the Valencia region of Spain during 1998–2018 and uses simulations with the Weather Research and Forecasting (WRF) model to study how extreme COL precipitation may change in a future warmer climate. COLs were shown to be the main producer of extreme precipitation in the Valencia region, especially during the transition seasons. The strongest raining COL events occurred during Se...| MDPI
Drones have become increasingly popular tools to study marine megafauna but are underutilized in batoid research. We used drones to collect video data of manta ray (Mobula cf. birostris) swimming and assessed behavior-specific kinematics in Kinovea, a semi-automated point-tracking software. We describe a ‘resting’ behavior of mantas making use of strong currents in man-made inlets in addition to known ‘traveling’ and ‘feeding’ behaviors. No significant differences were found betwe...| MDPI
Consumers have recently shown a preference for natural food products and ingredients and within that framework, their interest in consuming raw drinking milk has been highlighted, claiming nutritional, organoleptic and health benefits. However, a public debate has simultaneously emerged about the actual risks and benefits of direct human consumption of raw milk. This paper compares the microbiological, nutritional and sensory profile of raw and heat-treated milk, to evaluate the real risks an...| MDPI
Background/Objectives: A dietary pattern that simply reduces animal-based foods may be more acceptable to consumers than strict vegetarian or vegan diets. The objective of this investigation was to identify the most consistently used definitions of “flexitarian” dietary patterns, or dietary patterns with a reduced amount of animal foods. Then, sets of food-based dietary guidance (FBDG) from different countries and regions were evaluated to determine whether their guidance could accommodat...| MDPI
Located in the north-western part of Kyushu, “Hidden Christians Sites in the Nagasaki Region” were designated as a UNESCO World Heritage Site in 2018. This serial property consists of twelve sites, including the Christian villages that bear unique testimony to a cultural tradition nurtured under a long period of religious prohibition. Based on fieldwork research at Kirishitan villages in Hirado City, this paper shows how the global conservation strategies affect the local people and the s...| MDPI
The dairy industry is facing criticism for its role in exacerbating global GHG emissions, as climate change becomes an increasingly pressing issue. These emissions mostly originate from methane (CH4), nitrous oxide (N2O), and carbon dioxide (CO2). An optimal strategy involves the creation of an economical monitoring device to evaluate methane emissions from dairy animals. Livestock production systems encounter difficulties because of escalating food demand and environmental concerns. Enhancin...| MDPI
Ecology and the climate provide two perspectives of the same biogeophysical system at all spatiotemporal scales More effectively embracing this congruence is an opportunity to improve scientific understanding and predictions as well as for a more effective policy that integrates both the bottom-up community, business-driven framework, and the popular, top-down impact assessment framework. The objective of this paper is, therefore, to more closely integrate the diverse spectrum of scientists, ...| MDPI
Proper moisture is an essential condition for maintaining the homeostasis of the body, enhancing immunity, and preventing constipation, and it is an indispensable substance for maintaining human life and health. As the bacteria that cause oral disease are affected by water intake, there is a strong relationship between water intake and oral disease. Therefore, the purpose of this study is to determine the effect of daily water intake on oral disease. The data analyzed were from a seven-year p...| MDPI
The tropical coral Siderasterea radians is typically found in mangrove areas, seagrass beds, and environments tolerated by few other scleractinians in the Caribbean and South Florida. Siderastrea radians experience bleaching stress in Buttonwood Sound in Florida Bay during April–May, a time when the seawater is below bleaching temperatures. Stress first appears as a pink coloration due to the presence of fluorescent pigments protecting the coral tissue and algal symbionts from exposure to e...| MDPI
X-linked hypohidrotic ectodermal dysplasia (XLHED), caused by a genetic deficiency of ectodysplasin A1 (EDA1), is a rare developmental disorder of ectodermal derivatives such as hair, sweat glands, and teeth. The absence of sweat glands and perspiration can evoke life-threatening hyperthermia. As molecular genetic findings are not always conclusive, the concentrations of circulating EDA1 may help to distinguish between total and partial EDA1 deficiencies. We previously treated nine male patie...| MDPI
Extreme wildfire events are becoming more common and while the immediate risks of particulate exposures to susceptible populations (i.e., elderly, asthmatics) are appreciated, the long-term health effects are not known. In 2017, the Seeley Lake (SL), MT area experienced unprecedented levels of wildfire smoke from July 31 to September 18, with a daily average of 220.9 μg/m3. The aim of this study was to conduct health assessments in the community and evaluate potential adverse health effects....| MDPI
Lung involvement is the most common extraglandular manifestation of primary Sjögren’s Disease (pSjD). There is an increasing interest in finding the clinical/serological risk predictors of this feature. A cross-sectional study evaluating anti-SSA/Ro antibodies, anti-SSB/La antibodies, rheumatoid factor, antinuclear antibodies, and the diffusing capacity of the lungs for carbon monoxide (DLCO) in 26 pSjD patients who presented interstitial changes on the chest CT scan was performed. The tit...| MDPI
The burial of unbaptized fetuses and infants, as seen through texts and archaeology, exposes friction between the institutional Church and medieval Italy’s laity. The Church’s theology of Original Sin, baptism, and salvation left the youngest children especially vulnerable to dying unbaptized and subsequently being denied a Christian burial in consecrated grounds. We here present textual and archaeological evidence from medieval Italy regarding the tensions between canon law and parental ...| MDPI
Neurodiversity is a concept and a social movement that addresses and normalizes human neurocognitive heterogeneity to promote acceptance and inclusion of neuro-minorities (e.g., learning disabilities, attention disorders, psychiatric disorders, and more) in contemporary society. Neurodiversity is attributed to nature and nurture factors, and about a fifth of the human population is considered neurodivergent. What does neurodiversity mean neuroscientifically? This question forms the foundation...| MDPI
People have specific and unique individual and contextual characteristics, so healthcare should increasingly opt for person-centered care models. Thus, this review aimed to identify and synthesize the indicators for the care process of the person with depression and/or anxiety disorders, based on patient-centered care, going through the stages of diagnostic assessment and care planning, including intervention. An integrative literature review with research in seven scientific databases and a ...| MDPI
Neurodevelopmental disorders are a group of complex multifactorial disorders characterized by cognitive impairment, communication deficits, abnormal behaviour, and/or motor skills resulting from abnormal neural development. Copy number variants (CNVs) are genetic alterations often associated with neurodevelopmental disorders. We evaluated the diagnostic efficacy of the array-comparative genomic hybridization (a-CGH) method and its relevance as a routine diagnostic test in patients with neurod...| MDPI
Newcastle disease, caused by virulent strains of avian paramyxovirus 1 (APMV-1), occurs globally and has significant social and economic impact. APMV-1 is a rapidly evolving RNA virus and is genetically divided into class I and class II with almost all virulent viruses being of class II. The considerable genetic diversity of the virus adds complexity to maintaining the high sensitivity and specificity of molecular detection assays. The current USDA’s fusion gene rRT-PCR assay was designed f...| MDPI
Background and Objective: Fatigue represents a hallmark symptom in Multiple Sclerosis (MS), but its diagnosis and clinical evaluation is difficult because it is described as a subjective feeling of exhausted physical and mental sensation. Studies have also shown that approaches based on assisted therapies and robotics, as well as the use of vibration, which are used to improve sensory integration, reduce fatigue. The primary outcome in this study is to evaluate the effects of the application ...| MDPI
Background/Objectives: Randomized controlled trials (RCTs) are needed to evaluate the impact of food is medicine (FIM) programs, such as medically tailored groceries (MTGs) to treat hypertension among diverse populations. Partnerships between academic centers’ student-run organizations (SROs) and community-based organizations (CBOs) offer critical safety nets for historically underserved groups, positioning these organizations to effectively undertake FIM programs among populations dispropo...| MDPI
Cultured meat refers to the production of animal tissue by utilizing the same techniques as tissue engineering through cell culture. Various biomaterials have been designed to serve as in vitro supports for cell viability, growth, and migration. In this study, visible light and dual-crosslinked alginate hydrogels were designed to enable control of the physical and mechanical properties needed for the fabrication of cultured meat scaffolds. We hypothesized that a difference in hydrogel stiffne...| MDPI
Carrageenan (CGN) is a high molecular weight polysaccharide extracted from red seaweeds, composed of D-galactose residues linked in β-1,4 and α-1,3 galactose-galactose bond, widely used as a food additive in processed foods for its properties as a thickener, gelling agent, emulsifier, and stabilizer. In recent years, with the spread of the Western diet (WD), its consumption has increased. Nonetheless, there is a debate on its safety. CGN is extensively used as an inflammatory and adjuvant a...| MDPI
With widespread applications for lithium-ion batteries in energy storage systems, the performance degradation of the battery attracts more and more attention. Understanding the battery’s long-term aging characteristics is essential for the extension of the service lifetime of the battery and the safe operation of the system. In this paper, lithium iron phosphate (LiFePO4) batteries were subjected to long-term (i.e., 27–43 months) calendar aging under consideration of three stress factors ...| MDPI
Water is an essential resource for the realization of the United Nations’ 2030 Sustainable Development Goals. The increasing global food insecurity, hunger, human population, and uneconomical extraction and use of non-renewable resources require, among other things, a substantial intensification of agricultural production. In this context, there has been a need to adopt irrigation technologies, especially in developing countries where agriculture and its allied sectors employ more than 50% ...| MDPI
Spiritual Intelligence (SI) is the ability to draw on and embody spiritual qualities and resources to enhance daily functioning and wellbeing. Despite Gardner’s rejection of SI, the proliferation of SI models and research supporting the advantages of SI across a wide field of endeavors, and correlation with neurological structures and genetic indicators strongly support its validity as an intelligence. This article reviewed key models of SI, and studies supporting its adaptability and biolo...| MDPI
Coating technology, as a part of surface engineering, has shown remarkable potential in future industrial applications. With the continuous development and improvement of coating technology, coatings have gradually become an indispensable part of industrial manufacturing, possessing various excellent properties and characteristics, such as superhydrophobicity and self-cleaning, enhanced biological antibacterial properties, and improved corrosion resistance. Intelligent coatings are not only r...| MDPI
Hydrogen is currently enjoying a renewed and widespread momentum in many national and international climate strategies. This review paper is focused on analysing the challenges and opportunities that are related to green and blue hydrogen, which are at the basis of different perspectives of a potential hydrogen society. While many governments and private companies are putting significant resources on the development of hydrogen technologies, there still remains a high number of unsolved issue...| MDPI
In the fireworks industry (FI), many accidents and explosions frequently happen due to human error (HE). Human factors (HFs) always play a dynamic role in the incidence of accidents in workplace environments. Preventing HE is a main challenge for safety and precautions in the FI. Clarifying the relationship between HFs can help in identifying the correlation between unsafe behaviors and influential factors in hazardous chemical warehouse accidents. This paper aims to investigate the impact of...| MDPI
Background: Logistics service outsourcing in recent years has influenced the evolution of third-party logistics (3PL) providers across the globe. The study explored the evolving services of 3PLs and relational factors that influence the relationship with their customers. Methods: Qualitative research and multiple case studies from four different industries were used. Semi-structured interviews were adopted. Results: The findings show that aside from logistics and warehousing the customer expe...| MDPI
The sensory, volatile, and physiochemical profiles of nineteen commercial non-alcoholic pilsner-style beers produced by different production techniques were analyzed and compared with a dry-hopped non-alcoholic IPA. NABs made only with either physical dealcoholization or restricted fermentations differed significantly in chemistry and flavor. Generally, NABs produced by restricted fermentations were the most worty, thick, and sweet, whereas NABs that were physically dealcoholized had the lowe...| MDPI
The aerospike nozzle has emerged as a revolutionary technology in rocket propulsion, overcoming the limitations of conventional nozzles by dynamically adjusting the expansion of exhaust gases according to ambient pressure. This results in greater efficiency and fuel savings. Thanks to advancements in materials, computational simulations, and additive manufacturing, aerospike nozzle design has surpassed historical barriers, not only enhancing the performance of multi-stage engines but also ena...| MDPI
Social Networking Sites (SNSs) are virtual communities where users can create individual public profiles, interact with real-life friends, and meet other people based on shared interests. They are seen as a ‘global consumer phenomenon’ with an exponential rise in usage within the last few years. Anecdotal case study evidence suggests that ‘addiction’ to social networks on the Internet may be a potential mental health problem for some users. However, the contemporary scientific literat...| MDPI
Background: Cardiovascular diseases (CVDs) are leading global causes of mortality. Unhealthy diets have been linked to an increased risk of CVD, while plant-based diets have shown potential protective effects. This umbrella review summarizes the evidence on the association between vegetarian diets and cardiovascular and cerebrovascular diseases. Methods: PubMed, Scopus, Embase, CINAHL, Cochrane, and Web of Science were consulted. Meta-analyses grouped by author and outcome were performed. The...| MDPI
Background: Our previous comparison of peripheral blood mononuclear cells (PBMCs) from long-term Transcendental Meditation® (TM®) practitioners and matched non-practitioner controls found 200 differentially expressed (DE) genes. Bioinformatics analyses of these DE genes suggested a reduced risk of diseases associated with stress and aging in the TM group. Here we assessed additional signs of reduced stress and aging. Methods: A sample of 15 of the 200 DE genes was studied using qPCR in PBMC...| MDPI
Population aging has become a common problem all over the world, and the process of China’s population aging is developing rapidly. China has made active aging a national development strategy, giving full attention to the physical and mental health of the elderly. Bloodline and family continuity make the Chinese elderly attach great importance to the responsibility of caring for grandchildren. This study takes the elderly as the research center, and aims to investigate the relationship betw...| MDPI
The Arctic presents various challenges for a transition to electric vehicles compared to other regions of the world, including environmental conditions such as colder temperatures, differences in infrastructure, and cultural and economic factors. For this study, academic researchers partnered with three rural communities: Kotzebue, Galena, and Bethel, Alaska, USA. The study followed a co-production process that actively involved community partners to identify 21 typical vehicle use cases that...| MDPI
In recent years, there has been a growing interest in increasing motivational factors within the domain of psychology. Among these factors, Grit, Mindset, Self-Efficacy, and Well-Being (Flourishing) have been suggested to play an important role in individuals’ performance and Well-Being. Thus, cultivating these factors in the general population is important. Previous interventions have displayed substantial effects in certain areas. However, these interventions have primarily been Mindset o...| MDPI
There are more than thousands of concepts for harvesting wave energy, and wave energy converters (WECs) are diverse in operating principles, design geometries and deployment manners, leading to misconvergence in WEC technologies. Among numerous WEC devices, the point absorber wave energy converter (PAWEC) concept is one of the simplest, most broad-based and most promising concepts that has been investigated intensively all over the world. However, there are only a few reviews focusing on PAWE...| MDPI
Hereditary spastic paraplegias (HSPs) comprise a family of degenerative diseases mostly hitting descending axons of corticospinal neurons. Depending on the gene and mutation involved, the disease could present as a pure form with limb spasticity, or a complex form associated with cerebellar and/or cortical signs such as ataxia, dysarthria, epilepsy, and intellectual disability. The progressive nature of HSPs invariably leads patients to require walking canes or wheelchairs over time. Despite ...| MDPI
As part of the substantial public discourse surrounding the distribution and use of mifepristone, which is used with misoprostol to facilitate drug-induced abortions, claims comparing the safety of this regimen to that of common pharmaceuticals have emerged and proliferated. Offered in forums ranging from social media to the Supreme Court, these claims have so gained public acceptance that they are now echoed without scrutiny and, at times, reference. Yet the simplistic slogan that “mifepri...| MDPI
Among the multiple zoomorphic and geometric images that dominate Upper Paleolithic decorated cave walls in Europe, some intriguing human hand stencils and finger flutings stand out. Dozens of these marks are attributed to toddlers and children aged 2–12. Accompanied by older group members, they entered these deep, oxygen-depleted and sensory-deprived spaces, climbing and crawling in dark, wet, difficult-to-navigate environments where one might easily get lost or separated from the group. So...| MDPI
Personality changes have been reported following organ transplantation. Most commonly, such changes have been described among heart transplant recipients. We set out to examine whether personality changes occur following organ transplantation, and specifically, what types of changes occur among heart transplant recipients compared to other organ recipients. A cross-sectional study was conducted in which 47 participants (23 heart recipients and 24 other organ recipients) completed an online su...| MDPI
Epidemiological and clinical studies have indicated positive outcomes related to tree nut consumption. Here, we review the production, nutrient, phytochemical composition and emerging research trends on the health benefits of pistachio nuts (Pistacia vera L.). Pistachios are a good source of protein, fiber, monounsaturated fatty acids, minerals and vitamins, as well as carotenoids, phenolic acids, flavonoids and anthocyanins. Polyphenols in pistachios are important contributors to the antioxi...| MDPI
Since its introduction, aspartame—the leading sweetener in U.S. diet sodas (DS)—has been reported to cause neurological problems in some users. In prospective studies, the offspring of mothers who consumed diet sodas/beverages (DSB) daily during pregnancy experienced increased health problems. We hypothesized that gestational/early-life exposure to ≥1 DS/day (DSearly) or equivalent aspartame (ASPearly: ≥177 mg/day) increases autism risk. The case-control Autism Tooth Fairy Study obtai...| MDPI
The proliferation of artificial intelligence (AI) tools has transformed numerous aspects of daily life, yet its impact on critical thinking remains underexplored. This study investigates the relationship between AI tool usage and critical thinking skills, focusing on cognitive offloading as a mediating factor. Utilising a mixed-method approach, we conducted surveys and in-depth interviews with 666 participants across diverse age groups and educational backgrounds. Quantitative data were analy...| MDPI
Mainstream competitiveness and international development analyses pay little attention to the significance of a country’s resource security for its economic performance. This paper challenges this neglect, examining the economic implications of countries resource dynamics, particularly for low-income countries. It explores typologies of resource patterns in the context of those countries’ economic prospects. To begin, the paper explains why it uses Ecological Footprint and biocapacity acc...| MDPI
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Autism spectrum disorder (ASD), schizophrenia, and bipolar disorder are genetically complex and heterogeneous neurodevelopmental disorders (NDDs) resulting from genetic factors and gene-environment (GxE) interactions for which onset occurs in early brain development. Recent progress highlights the link between ASD and (i) immunogenetics, neurodevelopment, and inflammation, and (ii) impairments of autophagy, a crucial neurodevelopmental process involved in synaptic pruning. Among various envir...| MDPI
Anacondas, genus Eunectes, are a group of aquatic snakes with a wide distribution in South America. The taxonomic status of several species has been uncertain and/or controversial. Using genetic data from four recognized anaconda species across nine countries, this study investigates the phylogenetic relationships within the genus Eunectes. A key finding was the identification of two distinct clades within Eunectes murinus, revealing two species as cryptic yet genetically deeply divergent. Th...| MDPI
DNA impurities can impact the safety of genetically engineered pharmaceuticals; thus, a specific limit value must be set for them during marketing authorisation. This particularly applies to mRNA vaccines, as large quantities of DNA templates are used for their production. Furthermore, when quantifying the total DNA content in the final product, we must observe that, in addition to the mRNA active ingredient, DNA impurities are also encased in lipid nanoparticles and are therefore difficult t...| MDPI
Past studies have reported a decreasing planetary albedo and an increasing absorption of solar radiation by Earth since the early 1980s, and especially since 2000. This should have contributed to the observed surface warming. However, the magnitude of such solar contribution is presently unknown, and the question of whether or not an enhanced uptake of shortwave energy by the planet represents positive feedback to an initial warming induced by rising greenhouse-gas concentrations has not conc...| MDPI
This review raises a number of compelling issues related to the condition of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Some historical perspective is necessary in order to highlight the nature of the controversy concerning its causation. Throughout history, a pattern tends to repeat itself when natural phenomena require explanation. Dogma usually arrives first, then it is eventually replaced by scientific understanding. The same pattern is unfolding in relation to ME/CFS, b...| MDPI
The prevalence of autism has been increasing at an alarming rate. Even accounting for the expansion of autism spectrum disorder diagnostic (ASD) criteria throughout the 1990’s, there has been an over 300% increase in ASD prevalence since the year 2000. The often debilitating personal, familial, and societal sequelae of autism are generally believed to be lifelong. However, there have been several encouraging case reports demonstrating the reversal of autism diagnoses, with a therapeutic foc...| MDPI
Immortal time bias (ITB) is common in cohort studies and distorts the association estimates between the treated and untreated. We used data from an Italian study on COVID-19 vaccine effectiveness, with a large cohort, long follow-up, and adjustment for confounding factors, affected by ITB, with the aim to verify the real impact of the vaccination campaign by comparing the risk of all-cause death between the vaccinated population and the unvaccinated population. We aligned all subjects on a si...| MDPI
The influences of indoor plants on people have been examined by only three systematic reviews and no meta-analyses. The objective of this study was therefore to investigate the effects of indoor plants on individuals’ physiological, cognitive, health-related, and behavioral functions by conducting a systematic review with meta-analyses to fill the research gap. The eligibility criteria of this study were (1) any type of participants, (2) any type of indoor plants, (3) comparators without an...| MDPI
Natural hazards threaten millions of people all over the world. To address this risk, exposure and vulnerability models with high resolution data are essential. However, in many areas of the world, exposure models are rather coarse and are aggregated over large areas. Although OpenStreetMap (OSM) offers great potential to assess risk at a detailed building-by-building level, the completeness of OSM building footprints is still heterogeneous. We present an approach to close this gap by means o...| MDPI
Macroalgae, or seaweeds, are a rich source of components which may exert beneficial effects on the mammalian gut microbiota through the enhancement of bacterial diversity and abundance. An imbalance of gut bacteria has been linked to the development of disorders such as inflammatory bowel disease, immunodeficiency, hypertension, type-2-diabetes, obesity, and cancer. This review outlines current knowledge from in vitro and in vivo studies concerning the potential therapeutic application of sea...| MDPI
Little research has dealt with intragroup ancestry-related differences in intelligence in Black and White Americans. To help fill this gap, we examined the association between intelligence and both color and parent-reported ancestry using the NLSY97. We used a nationally-representative sample, a multidimensional measure of cognitive ability, and a sibling design. We found that African ancestry was negatively correlated with general mental ability scores among Whites (r = −0.038, N = 3603; c...| MDPI
Concerns about the well-being of lawyers are rising against the backdrop of a transforming legal profession, one which many observe to be operating more like a business in recent decades. However, aspects of this change, such as lawyers perceiving that their employers value financial performance and productivity above all else, could be associated with unhealthy work practices detrimental to lawyer well-being. The objective of the present study was to determine whether the perceived values of...| MDPI
This study focuses on cardiovascular manifestation, particularly myocarditis and pericarditis events, after BNT162b2 mRNA COVID-19 vaccine injection in Thai adolescents. This prospective cohort study enrolled students aged 13–18 years from two schools, who received the second dose of the BNT162b2 mRNA COVID-19 vaccine. Data including demographics, symptoms, vital signs, ECG, echocardiography, and cardiac enzymes were collected at baseline, Day 3, Day 7, and Day 14 (optional) using case reco...| MDPI
The book and film franchise of Harry Potter has inspired a monumental fandom community with a veracious output of fanfiction and general musings on the text and the vivid universe contained therein. A significant portion of these texts deal with Professor Severus Snape, the stern Potions Master with ambiguous ethics and loyalties. This paper explores a small community of Snape fans who have gone beyond a narrative retelling of the character as constrained by the work of Joanne Katherine Rowli...| MDPI
The size of the world’s population has profound implications for demand for food, energy and resources, land use change and greenhouse gas emissions. This study examines why most population projections have underestimated world population growth, and the implications for actions required to achieve sustainable societies. The main determinant of future population is family size choices. Population projections by different research groups embed different assumptions about drivers of fertility...| MDPI
This work presents an estimation of the global electricity usage that can be ascribed to Communication Technology (CT) between 2010 and 2030. The scope is three scenarios for use and production of consumer devices, communication networks and data centers. Three different scenarios, best, expected, and worst, are set up, which include annual numbers of sold devices, data traffic and electricity intensities/efficiencies. The most significant trend, regardless of scenario, is that the proportion...| MDPI
